RHABDOMYOSARCOMA APPEAL
Registered Charity Number 1085775
Update Update June 10th 2008
Our MissionThe Chris
Lucas Trust is established to raise sufficient funds for a Scientific Researcher.
To encourage and support high quality research into Rhabdomyosarcoma, (a very aggressive cancer), with the aim of maintaining and improving human health.
To
help improve the quality of life of children and young adults.
To
advance scientific research and disseminate knowledge of research
findings to help other types of cancers with the aim of meeting national
needs in terms of health, quality of life of children and young adults.
To
promote public engagement with medical research.
To
work in collaboration with all medical staff to ensure that the Chris
Lucas Trust aims and objectives are adhered to, achieved.
Senior Post Doctoral Scientist
Since September 2005 our appointment of a senior post doctoral scientist to work exclusively on Rhabdomyosarcoma (RMS), he is Italian, based at the Royal Marsden Hospital, London, Institute of Cancer Research, Innovative Therapies for Children with Cancer (ITCC)
He has very good experience of molecular profiling of cancers and I am sure he will really help us push forward our ongoing work on rhabdomyosarcoma.
The research group is also very interested in the underlying molecular abnormalities in RMS that might be important as targets for developing new drugs.
Our vital work work on the molecular characterision of rhabdomyosarcoma, using 'microarray' profiling which tests thousands of genes simultaneously.
By looking at how these results predict response to
treatment, we aim to highlight the important genes for
choosing new drugs to test on RMS cell lines and in the
clinic and aim to identify new targets for
developing new drugs.
Chris Lucas Trust says "the costs of doing these types of
experiments is expensive, as is the amount needed to
keep a scientist working at the bench using modern
molecular techniques.
We desperately need vital donations to ensure the
continuous work of our Senior Researcher".
The funding is over £210,000 for three years (about
$368,000)
It is so expensive but unfortunately these are the costs
of modern molecular medicine".
Rhabdomyosarcoma (Rhab
– do – my – o - sarcoma) is
one of the most aggressive out of the various types over
400 types of cancers.
It is a disease in which cancer
(malignant) cells begin growing in muscle tissue anywhere in the body.
There are several types of Sarcoma that
are found in children and young adults. The cancer cells must be looked
at under a microscope to tell which type of sarcoma it is. It accounts
for approximately 3.5% of the cases of cancer among young children 0 to
14 years, and 2% of the cases among adolescents and young adults 15 to
19 years of age. It is a curable decease in the majority of children who
receive optimal therapy with more than surviving 5 years after
diagnosis.
The most common primary sites for
Rhabdomyosarcoma are the head and neck, other less common sites include
the trunk, intrathoracic region, the gastrointestinal tract and the
extremities (arms, legs) intestines, including liver and biliary
tract, and the perineal/anal region.
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Please send all donation to any United Kingdom Lloyds TSB bank account 'Chris Lucas Trust'
Sort Code: 30.96.15,
Account Number: 0815268
